Statistical consulting · pharma · actuarial · data analytics

Turning data into
clear, defensible decisions.

Data in. Clarity out.

Sinhara Analytics partners with pharma, actuarial teams, and data-heavy organizations— from labs to small businesses—that need rigorous statistics and probability modeling, not black boxes.

Your data shouldn’t sit in a spreadsheet. We turn it into decisions.

Led by two PhD statisticians with experience in probability models, variable selection, sample size planning, assay data, actuarial-style risk modeling, and complex analytics in R.

Who we are

Statisticians who live in your data.

Sinhara Analytics is a husband–wife statistics team based in North Carolina. We bring together years of teaching, research, and consulting to help teams frame the right questions, choose appropriate methods, and explain results in plain language.

Our work spans probability modeling, regression, variable selection, and data exploration in pharma, actuarial, and other data-rich environments. We are comfortable working with scientists, analysts, actuaries, decision-makers, and small-business owners—and we focus on solutions that are statistically sound and operationally useful.

  • PhD-level training in Statistics
  • Experience with pharmaceutical and laboratory data
  • Methodological work in penalized regression, variable selection, and robust modeling
  • Actuarial-style risk and probability modeling (SOA exam backgrounds)
  • Deep, production-level workflows in R
Leadership

Principals

Dr. Hasthika Rupasinghe · Statistical modeling, variable selection and penalized regression, probability modeling, and machine learning in R. Hasthika has passed SOA Exam P (Probability) and SOA Exam SRM (Statistics for Risk Modeling).

Dr. Lasanthi Watagoda · Variable selection, unsupervised learning (e.g., clustering, PCA, dimension reduction), study design, variability assessment, and interpretation and communication. Lasanthi has passed SOA Exams P, FM, and SRM.

Together, we provide end-to-end support—from “we just have a spreadsheet” to “we need a defensible analysis and clear recommendations.”

What we do

Services for data-heavy questions.

We work on both narrowly defined analyses and open-ended “we have data and questions” problems. Arrangements can be project-based, hourly, or ongoing, and we’re happy to support both larger organizations and small businesses.

View example case studies →

Probability & Risk Modeling

Support for probability-driven questions, especially in pharma and actuarial settings.

  • Probability models for quality, safety, and performance
  • Scenario and risk analysis under uncertainty
  • Stochastic simulation and what-if analysis
  • Translation of probability results into practical decisions

Statistical Modeling in R

Modern regression and modeling, implemented with reproducible R workflows.

  • Linear and generalized linear models
  • Penalized regression (Lasso, Elastic Net, Adaptive Lasso, AHRLR)
  • Tree-based and ensemble methods (e.g., decision trees, boosted models)
  • Nonlinear models when appropriate (including 4PL and relatives)

Design, Sample Size & Data Consulting

Help at the planning and “messy data” stages—before, during, or after a study or project, for both established teams and small businesses.

  • Sample size and power calculations for studies and experiments
  • High-level study design and analysis planning
  • Exploratory data analysis, cleaning, and structuring
  • Any data-related problem where you need a statistical partner
Areas of expertise

Where we add the most value.

These are some of the settings where our blend of probability, modeling, and data skills tends to be especially useful—including work with pharma, actuarial teams, and data-rich small businesses.

Pharma & Life Sciences

  • Assay data analysis and variability assessment
  • Probability-based questions about failure, success, and risk
  • Support for validation and comparability work
  • Clear, statistics-grounded narratives for internal stakeholders

Actuarial & Decision Support

  • Support for actuarial teams on probability, risk, and SRM-style questions
  • Decision trees and other interpretable models for choices under uncertainty
  • Scenario analysis, sensitivity analysis, and trade-off exploration
  • Helping teams choose between competing options using data

Training & Team Uplift

  • Short-format workshops on R and statistical thinking
  • Walkthroughs of analysis pipelines for your team
  • Code review and workflow suggestions in R
  • Best practices for reproducible analysis within your context

Example: decision tree for a dosing decision

Baseline metric Low response High response A B C D
A simple, stylized decision tree: we often use interpretable models like this to support “if we choose X, what happens?” discussions.

Example: probability curves over dose levels

Dose Probability Scenario 1 Scenario 2
A stylized example of probability curves across dose or setting levels: we frequently visualize scenarios to help teams reason about risk and trade-offs.
Visual outputs

How we like to see data.

We emphasize visualizations that make variability, uncertainty, and differences easy to see—whether that’s distributions, dose–response relationships, model comparisons, or patterns in data from small or large teams.

Example: colorful boxplots across groups

Group 1 Group 2 Group 3
Boxplots are a simple way to show distributions and variability across groups, batches, or conditions.

Example: 4PL reference vs test curves

Log dose Response Reference Test
When 4PL models are appropriate, we visualize reference and test curves together to make shifts and differences easy to see.
How we work

A clear, collaborative process.

Whether you have a fully specified question or just “a lot of data,” we follow a structured process with room for discussion and iteration. This applies equally well to pharma projects, actuarial work, and small-business analytics.

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Step 1
Initial conversation

We review your goals, your data (or planned data), and your timelines to see if we’re a good fit and what level of support makes sense.

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Step 2
Proposal & scope

You receive a written scope of work, including questions to be addressed, methods we anticipate using, a timeline, and fees.

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Step 3
Analysis & check-ins

We carry out the analyses in R, sharing interim results and discussing modeling choices, assumptions, and alternative scenarios as needed.

Step 4
Deliverables & follow-up

You receive a clear summary of findings, supporting figures and tables, and (when appropriate) R code or scripts, plus time for Q&A with your team.

Client feedback

What collaborators say.

Representative comments from teams we have supported. Full references available on request.

Sinhara Analytics helped us frame the right probability questions and interpret the results in a way our scientists and leadership could act on. Their work strengthened our decisions and our confidence in them.

Director of Analytical Development
Biotech client (US)

They took a messy, high-dimensional dataset and turned it into clear, defensible findings. We appreciated both the rigor of the analysis and the clarity of the explanations.

R&D Team Lead
Pharma client
Get in touch

Tell us about your data and decisions.

Share a brief description of your data (or planned data), your key questions, and any timelines. We work with pharma and biotech teams, actuarial groups, and data-driven small businesses. We’ll respond with suggested next steps and, if appropriate, a time for a short introductory call.

Prefer email? You can reach us directly at
info@sinharaanalytics.com

We are based in North Carolina and work with clients across the United States and internationally.

Not sure how to describe your problem yet? That’s fine. Tell us what decisions you’re facing and what data you have, whether you’re in pharma, an actuarial group, or a small business, and we’ll help you connect the two.